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Patrick O'Shaughnessy

Host of the Invest Like the Best podcast; CEO of Positive Sum

The latest interviews, podcast appearances, and blog posts from Patrick O'Shaughnessy, updated daily.

All26Video12Podcast14Post0Content from April 2026 onward
3 months ago
Aug 18

What Happens When the AI Boom Runs Out of Money

Ben Thompson joins Invest Like the Best for a wide-ranging conversation about the economics, geopolitics, and business models shaping the AI era. They discuss why overwhelming U. S.

Invest Like The Best
3 months ago
Aug 11

Everyone Is Still Undersizing the AI Market | Eric Vishria

Eric Vishria, General Partner at Benchmark, joins Invest Like the Best for a wide-ranging conversation on how AI is reshaping software, infrastructure, and venture investing.

Invest Like The Best
3 months ago
Jul 28

Sam Altman - How to Make an Abundant Future - [Invest Like the Best, EP.484]

Sam Altman is the CEO of OpenAI. We cover the compute buildout that wasn't reckless enough, why ChatGPT was never supposed to be a product, and the…

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jul 21

Matthew Smith — Natural Gas: The Next Bottleneck - [Invest Like the Best, EP.483]

Matthew Smith is the founder and CIO of Chronometer Partners.

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jul 14

John Kim - How to Raise a Few Billion Dollars - [Invest Like the Best, EP.482]

John Kim is the Chairman of Lila Sciences and the author of The Tao of Fundraising.

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jul 7

Jeremy Giffon - The Billion Dollar PDF - [Invest Like the Best, EP.481]

Jeremy Giffon is the founder of Octave. We cover how society has become subservient to the posting class, why nearly every white-collar job is made…

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jun 30

Etched - Building AI Hardware to Make Inference Faster and Cheaper - [Invest Like the Best, EP.480]

Gavin Uberti and Rob Wachen are co-founders of Etched.

Invest Like the Best with Patrick O'Shaughnessy
5 months ago
Jun 23

Vlad Barbalat - Investing $120 Billion in Permanent Capital - [Invest Like the Best, EP.479]

Vlad Barbalat is the Chief Investment Officer of Liberty Mutual Investments.

Invest Like the Best with Patrick O'Shaughnessy
5 months ago
Jun 16

Kareem Amin - The Unusual Approach to Company Building - [Invest Like the Best, EP.478]

Kareem Amin is the co-founder and CEO of Clay.

Invest Like the Best with Patrick O'Shaughnessy
5 months ago
Jun 9

Alex Sacerdote - How to Invest Through Technology Cycles - [Invest Like the Best, EP.477]

Alex Sacerdote is the founder of Whale Rock Capital Management.

Invest Like the Best with Patrick O'Shaughnessy
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