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Patrick O'Shaughnessy

Host of the Invest Like the Best podcast; CEO of Positive Sum

The latest interviews, podcast appearances, and blog posts from Patrick O'Shaughnessy, updated daily.

All26Video12Podcast14Post0Content from April 2026 onward
5 weeks ago
Sep 28

Inside the Personal AI Assistant Growing 10% a Day | Instinct Founder

Some invites to Instinct for our listeners: Patrick O'Shaughnessy interviews Noah Shinn, CEO of Instinct, the viral AI personal assistant taking the tech world by storm.

Invest Like The Best
6 weeks ago
Sep 22

Why OpenAI and Anthropic Won't Win Finance

Gabe Stengel is the co-founder of Rogo, an AI platform built for financial institutions.

Invest Like The Best
2 months ago
Aug 25

Ex-NVIDIA Engineer: Why AI Is About to Get 1000x Cheaper

Neil Movva, co-founder of Sail Research, joins Patrick to explain why the next era of AI may be defined not by faster chatbots, but by background agents that work autonomously for hours, days, or even…

Invest Like The Best
3 months ago
Aug 18

What Happens When the AI Boom Runs Out of Money

Ben Thompson joins Invest Like the Best for a wide-ranging conversation about the economics, geopolitics, and business models shaping the AI era. They discuss why overwhelming U. S.

Invest Like The Best
3 months ago
Aug 11

Everyone Is Still Undersizing the AI Market | Eric Vishria

Eric Vishria, General Partner at Benchmark, joins Invest Like the Best for a wide-ranging conversation on how AI is reshaping software, infrastructure, and venture investing.

Invest Like The Best
3 months ago
Jul 28

Sam Altman - How to Make an Abundant Future - [Invest Like the Best, EP.484]

Sam Altman is the CEO of OpenAI. We cover the compute buildout that wasn't reckless enough, why ChatGPT was never supposed to be a product, and the…

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jul 21

Matthew Smith — Natural Gas: The Next Bottleneck - [Invest Like the Best, EP.483]

Matthew Smith is the founder and CIO of Chronometer Partners.

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jul 14

John Kim - How to Raise a Few Billion Dollars - [Invest Like the Best, EP.482]

John Kim is the Chairman of Lila Sciences and the author of The Tao of Fundraising.

Invest Like the Best with Patrick O'Shaughnessy
5 months ago
Jun 16

Kareem Amin - The Unusual Approach to Company Building - [Invest Like the Best, EP.478]

Kareem Amin is the co-founder and CEO of Clay.

Invest Like the Best with Patrick O'Shaughnessy
5 months ago
Jun 3

Dara Khosrowshahi - Uber's Bet on AVs, AI, and Building a Super-App - [Invest Like the Best, EP.476]

Dara Khosrowshahi is the CEO of Uber. We cover what leaving Iran aged nine taught him about dealing with pressure, Uber's push to become the leading…

Invest Like the Best with Patrick O'Shaughnessy
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