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Patrick O'Shaughnessy

Host of the Invest Like the Best podcast; CEO of Positive Sum

The latest interviews, podcast appearances, and blog posts from Patrick O'Shaughnessy, updated daily.

All26Video12Podcast14Post0Content from April 2026 onward
2 days ago
Nov 4

Martin Casado on Frontier Model Economics, AI's Slowdown, and the Cursor Deal - [Invest Like the Best, EP.498]

Martin Casado is a General Partner at Andreesen Horowitz.

Invest Like the Best with Patrick O'Shaughnessy
10 days ago
Oct 27

Cliff Sosin - Owning the Complements to Intelligence - [Invest Like the Best, EP.497]

Cliff Sosin is the founder of CAS Investment Partners.

Invest Like the Best with Patrick O'Shaughnessy
17 days ago
Oct 20

Christina Cacioppo - Building an Enduring Software Company in the Age of AI - [Invest Like the Best, EP.496]

Christina Cacioppo is the founder and CEO of Vanta.

Invest Like the Best with Patrick O'Shaughnessy
24 days ago
Oct 13

David Vélez - Building Nubank and the Future of Global Banking - [Invest Like the Best, EP.495]

David Vélez is the founder and CEO of Nubank.

Invest Like the Best with Patrick O'Shaughnessy
4 weeks ago
Oct 6

Andrew Huberman - The Frontier of Neurotechnology - [Invest Like the Best, EP.494]

Andrew Huberman is a neuroscientist and professor at Stanford University.

Invest Like the Best with Patrick O'Shaughnessy
7 weeks ago
Sep 16

Michael Moritz - Lessons From 40 Years of Investing and Writing - [Invest Like the Best, EP.491]

Michael Moritz is a writer and former partner at Sequoia Capital.

Invest Like the Best with Patrick O'Shaughnessy
8 weeks ago
Sep 8

Walter Russell Mead - How America Keeps Winning - [Invest Like the Best, EP.490]

Walter Russell Mead is a columnist for the Wall Street Journal.

Invest Like the Best with Patrick O'Shaughnessy
2 months ago
Sep 1

Sarah Guo - Funding the Frontier - [Invest Like the Best, EP.489]

Sarah Guo is the founder of Conviction. We cover what she's learned from studying the 250 most important AI builders, why compute independence…

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jul 7

Jeremy Giffon - The Billion Dollar PDF - [Invest Like the Best, EP.481]

Jeremy Giffon is the founder of Octave. We cover how society has become subservient to the posting class, why nearly every white-collar job is made…

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
Jun 30

Etched - Building AI Hardware to Make Inference Faster and Cheaper - [Invest Like the Best, EP.480]

Gavin Uberti and Rob Wachen are co-founders of Etched.

Invest Like the Best with Patrick O'Shaughnessy
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