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Patrick O'Shaughnessy

Host of the Invest Like the Best podcast; CEO of Positive Sum

The latest interviews, podcast appearances, and blog posts from Patrick O'Shaughnessy, updated daily.

All19Video10Podcast9Post0Content from April 2026 onward
5 days ago
Sep 16

Michael Moritz - Lessons From 40 Years of Investing and Writing - [Invest Like the Best, EP.491]

Michael Moritz is a writer and former partner at Sequoia Capital.

Invest Like the Best with Patrick O'Shaughnessy
13 days ago
Sep 8

Walter Russell Mead - How America Keeps Winning - [Invest Like the Best, EP.490]

Walter Russell Mead is a columnist for the Wall Street Journal.

Invest Like the Best with Patrick O'Shaughnessy
20 days ago
Sep 1

Sarah Guo - Funding the Frontier - [Invest Like the Best, EP.489]

Sarah Guo is the founder of Conviction. We cover what she's learned from studying the 250 most important AI builders, why compute independence…

Invest Like the Best with Patrick O'Shaughnessy
3 months ago
Jul 7

Jeremy Giffon - The Billion Dollar PDF - [Invest Like the Best, EP.481]

Jeremy Giffon is the founder of Octave. We cover how society has become subservient to the posting class, why nearly every white-collar job is made…

Invest Like the Best with Patrick O'Shaughnessy
3 months ago
Jun 30

Etched - Building AI Hardware to Make Inference Faster and Cheaper - [Invest Like the Best, EP.480]

Gavin Uberti and Rob Wachen are co-founders of Etched.

Invest Like the Best with Patrick O'Shaughnessy
3 months ago
Jun 23

Vlad Barbalat - Investing $120 Billion in Permanent Capital - [Invest Like the Best, EP.479]

Vlad Barbalat is the Chief Investment Officer of Liberty Mutual Investments.

Invest Like the Best with Patrick O'Shaughnessy
3 months ago
Jun 9

Alex Sacerdote - How to Invest Through Technology Cycles - [Invest Like the Best, EP.477]

Alex Sacerdote is the founder of Whale Rock Capital Management.

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
May 20

Gavin Baker - Watts and Wafers - [Invest Like the Best, EP.473]

Gavin Baker is the Managing Partner and CIO of Atreides Management.

Invest Like the Best with Patrick O'Shaughnessy
4 months ago
May 13

Krishna Rao - Anthropic's CFO on Compute, Scaling to $30B ARR, and the Returns to Frontier Intelligence - [Invest Like the Best, EP.472]

Krishna Rao is the CFO of Anthropic. We cover how Anthropic procures and allocates compute, the lived experience of operating one of the fastest…

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